Disease-modifying anti-rheumatic drugs (DMARDs) do more than simply treat the symptoms of JIA. They work by addressing the underlying causes of inflammation in the body, stabilising the activity of the immune system.
Methotrexate is the most commonly used DMARD in the treatment of JIA. It has been used for over 30 Years and has been shown in studies to benefit the majority of children treated with it. For many children, it is a key element in managing their condition, and most children who move on to treatment with the newer biologic drugs are encouraged to take them in combination with methotrexate.
It may be taken orally in tablet or liquid form or by injection, usually with a prefilled pen device.
If your child is taking methotrexate, keep in mind that:
Parents of older children taking methotrexate should also urge them to take special care if they drink alcohol or are sexually active.